BDBM16645 4-Propionamido-benzenesulfonamide::CHEMBL278395::N-(4-sulfamoylphenyl)propanamide::aromatic sulfonamide compound 10

SMILES CCC(=O)Nc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=KEFCIQSZJXXOLO-UHFFFAOYSA-N

Data  8 KI

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 16645   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16645(4-Propionamido-benzenesulfonamide | CHEMBL278395 |...)
Affinity DataKi:  56nMAssay Description:Inhibitiory activity against human Carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16645(4-Propionamido-benzenesulfonamide | CHEMBL278395 |...)
Affinity DataKi:  106nMAssay Description:Inhibitiory activity against human Carbonic anhydrase IX (hCA IX)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mus musculus (mouse))
Universita Degli Studi Di Firenze

LigandPNGBDBM16645(4-Propionamido-benzenesulfonamide | CHEMBL278395 |...)
Affinity DataKi:  210nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM16645(4-Propionamido-benzenesulfonamide | CHEMBL278395 |...)
Affinity DataKi:  232nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM16645(4-Propionamido-benzenesulfonamide | CHEMBL278395 |...)
Affinity DataKi:  232nMAssay Description:Inhibitiory activity against human Carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universita Degli Studi Di Firenze

LigandPNGBDBM16645(4-Propionamido-benzenesulfonamide | CHEMBL278395 |...)
Affinity DataKi:  2.63E+3nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16645(4-Propionamido-benzenesulfonamide | CHEMBL278395 |...)
Affinity DataKi:  1.97E+4nMAssay Description:Inhibitiory activity against human Carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16645(4-Propionamido-benzenesulfonamide | CHEMBL278395 |...)
Affinity DataKi:  1.97E+4nM ΔG°:  -6.41kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed