BDBM167415 US9073893, 8
SMILES CN1CCC(CC1)n1[nH]c2cccc(C(N)=O)c2c1=O
InChI Key InChIKey=SBXCLTZHGFAEGE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 167415
Affinity DataKd: 140nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair