BDBM167515 US9073917, 12- comparative

SMILES CCOC(=O)c1[nH]cc2[C@@H](c3ccc(Sc4nc5ccccc5[nH]4)o3)C3=C(CCCC3=O)Nc12

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 167515   

TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50:  3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50:  68nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50:  4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent