BDBM17000 Indolinone based compound, 7i::[(3Z)-3-{[4-(3-methylphenyl)-1H-pyrrol-2-yl]methylidene}-2-oxo-2,3-dihydro-1H-indol-5-yl]urea

SMILES Cc1cccc(c1)-c1c[nH]c(\C=C2/C(=O)Nc3ccc(NC(N)=O)cc23)c1

InChI Key InChIKey=HAWIAGQHDCBUDW-ZDLGFXPLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17000   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17000(Indolinone based compound, 7i | [(3Z)-3-{[4-(3-met...)
Affinity DataIC50:  37nMAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed