BDBM17013 Indolinone based compound, 21::N-[(5-{1-[(3Z)-5-(carbamoylamino)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]ethyl}-1H-pyrrol-3-yl)methyl]-2-hydroxyacetamide

SMILES C\C(=C1\C(=O)Nc2ccc(NC(N)=O)cc12)c1cc(CNC(=O)CO)c[nH]1

InChI Key InChIKey=UQSUHZYCCQIWGQ-SXGWCWSVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17013   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17013(Indolinone based compound, 21 | N-[(5-{1-[(3Z)-5-(...)
Affinity DataIC50:  10nMAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed