BDBM170546 US9085549, 57::US9085549, 64

SMILES Oc1ccc(cc1O)-c1nsc(n1)-c1ccc(O)c(O)c1

InChI Key InChIKey=MKKIWISQFSVGQX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 170546   

TargetAlpha-synuclein(Homo sapiens (Human))
Proteotech

US Patent
LigandPNGBDBM170546(US9085549, 57 | US9085549, 64)
Affinity DataKi:  89nMpH: 7.4Assay Description:The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Proteotech

US Patent
LigandPNGBDBM170546(US9085549, 57 | US9085549, 64)
Affinity DataKi:  124nMpH: 7.4Assay Description:The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Proteotech

US Patent
LigandPNGBDBM170546(US9085549, 57 | US9085549, 64)
Affinity DataIC50:  1.76E+4nMAssay Description:The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Proteotech

US Patent
LigandPNGBDBM170546(US9085549, 57 | US9085549, 64)
Affinity DataIC50:  1.02E+4nMAssay Description:The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...More data for this Ligand-Target Pair
In DepthDetails US Patent