BDBM173678 US9102591, N-((4,4-difluoro-1-(6-(trifluoromethyl)pyridin-3-yl)cyclohexyl)methyl)-3-methoxy-2-methylbenzamide::US9649308, N-((4,4-difluoro-1-(6-(trifluoromethyl)pyridin-3-yl)cyclohexyl)methyl)-3-methoxy-2-methylbenzamide

SMILES COc1cccc(C(=O)NCC2(CCC(F)(F)CC2)c2ccc(nc2)C(F)(F)F)c1C

InChI Key InChIKey=RPAIGIKQGNSHLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173678   

TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173678(US9102591, N-((4,4-difluoro-1-(6-(trifluoromethyl)...)
Affinity DataIC50:  1.60nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173678(US9102591, N-((4,4-difluoro-1-(6-(trifluoromethyl)...)
Affinity DataIC50:  1.60nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent