BDBM173820 US9102591, (+)2-chloro-N-[2-(4-fluorophenyl)-2-[6-(trifluoromethyl)-3-pyridyl]ethyl]benzamide::US9102591, (-)2-chloro-N-[2-(4-fluorophenyl)-2-[6-(trifluoromethyl)-3-pyridyl]ethyl]benzamide::US9649308, (-)2-chloro-N-[2-(4-fluorophenyl)-2-[6-(trifluoromethyl)-3-pyridyl]ethyl]benzamide

SMILES Fc1ccc(cc1)C(CNC(=O)c1ccccc1Cl)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=LMJIEFGCCUMUAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 173820   

TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173820(US9102591, (+)2-chloro-N-[2-(4-fluorophenyl)-2-[6-...)
Affinity DataIC50:  2.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173820(US9102591, (+)2-chloro-N-[2-(4-fluorophenyl)-2-[6-...)
Affinity DataIC50:  3.10nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173820(US9102591, (+)2-chloro-N-[2-(4-fluorophenyl)-2-[6-...)
Affinity DataIC50:  2.20nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173820(US9102591, (+)2-chloro-N-[2-(4-fluorophenyl)-2-[6-...)
Affinity DataIC50:  3.10nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent