BDBM176593 US9120761, 7

SMILES CCN1CCC(CC1)c1ccc(Nc2ncc(c(Cc3ccccc3C(N)=O)n2)C(F)(F)F)c(OC)c1

InChI Key InChIKey=OVSGTWVJEXAGQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176593   

TargetVascular endothelial growth factor receptor 3 [818-948,1003-1077](Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM176593(US9120761, 7)
Affinity DataIC50:  1.33E+4nMpH: 7.4Assay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Mus musculus (Mouse))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM176593(US9120761, 7)
Affinity DataIC50:  9.40nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2) S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent