BDBM17759 (2S)-2-(phosphonomethyl)pentanedioic acid::(S)-2-PMPA::pentanedioic acid analogue, (S)-1
SMILES OC(=O)CC[C@H](CP(O)(O)=O)C(O)=O
InChI Key InChIKey=ISEYJGQFXSTPMQ-SCSAIBSYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 17759
Affinity DataKi: 0.100nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of GCPII (unknown origin) NAALADase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of PSMA in human LNCaP cell extracts using NAAG as substrate by amplex red reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of GCPII (unknown origin) expressed in DU-145 cells after 2 hrs by Amplex red reagent based fluorescence assayMore data for this Ligand-Target Pair