BDBM177922 US10307413, Compound 337::US10391089, Compound 166::US10980794, Cmpd No 166::US11591326, Compound C1::US9675614, 166

SMILES O[C@@H](CNC(=O)c1cc(NC2COC2)ncn1)CN1CCc2ccccc2C1

InChI Key InChIKey=ZKXZLIFRWWKZRY-KRWDZBQOSA-N

Data  20 IC50  1 Kd

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177922   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Pharmablock Sciences (Nanjing)

US Patent
LigandPNGBDBM177922(US10307413, Compound 337 | US10391089, Compound 16...)
Affinity DataIC50:  85nMAssay Description:General Procedure for PRMT5/MEP50 AlphaLISA Enzyme Inhibitory Assays: Assays were performed in the buffer consisting of 50 mM Tris, pH 8.5, 5 mM MgCl...More data for this Ligand-Target Pair