BDBM177926 US9120797, 24::US9120797, 25

SMILES CN(C)C1(CCC2(CC1)OCCc1c2[nH]c2ccc(F)cc12)c1ccccc1

InChI Key InChIKey=CSMVOZKEWSOFER-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 177926   

TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177926(US9120797, 24 | US9120797, 25)
Affinity DataKi:  1.5nM ΔG°:  -12.0kcal/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177926(US9120797, 24 | US9120797, 25)
Affinity DataKi:  2.90nM ΔG°:  -11.6kcal/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177926(US9120797, 24 | US9120797, 25)
Affinity DataKi:  12nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177926(US9120797, 24 | US9120797, 25)
Affinity DataKi:  22nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent