BDBM18073 (2S)-2-amino-3-phenylpropanoic acid::CHEMBL301523::L-[2,3,4,5,6-3H]phenylalanine::L-phenylalanine::Phenylalanine::US11021454, Compound L-phe
SMILES N[C@@H](Cc1ccccc1)C(O)=O
InChI Key InChIKey=COLNVLDHVKWLRT-QMMMGPOBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 18073
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 980nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
TargetLarge neutral amino acids transporter small subunit 1(Rattus norvegicus)
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:Inhibition of LAT1-mediated L-[14C]-leucine uptake in Sprague-Dawley rat brain by duel-labeled liquid scintillation countingMore data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 2 hits for monomerid = 18073
ITC DataΔG°: -0.717kcal/mole −TΔS°: 2.14kcal/mole ΔH°: -2.87kcal/mole logk: 3
pH: 5.01 T: 25.00°C
pH: 5.01 T: 25.00°C
ITC DataΔG°: -1.24kcal/mole −TΔS°: 1.64kcal/mole ΔH°: -2.87kcal/mole logk: 8
pH: 5.01 T: 25.00°C
pH: 5.01 T: 25.00°C