BDBM181012 US9133197, 4
SMILES C[C@@H](O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1
InChI Key InChIKey=HMSFWLUZEDMXMM-SSDOTTSWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 181012
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMpH: 7.4Assay Description:The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...More data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in HEK293 cells assessed as inhibition of NECA-induced cAMP accumulation incubated for ...More data for this Ligand-Target Pair