BDBM18136 ADP, alpha beta-me::AMPCPP::[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl]phosphonic acid::alpha, beta-methyleneadenosine 5 -diphosphate::cid_92199
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O
InChI Key InChIKey=OLCWZBFDIYXLAA-IOSLPCCCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 18136
Affinity DataKi: 510nMAssay Description:Inhibition of CD73 in human melanoma 1539 cells using AMP substrate by capillary electrophoresis assayMore data for this Ligand-Target Pair
Affinity DataKi: 870nMAssay Description:Inhibition of rat CD73 expressed in baculovirus infected insect cells using AMP substrate by capillary electrophoresis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 10 mins followed by substrate addition and measured every min...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human C-terminal His6-tagged CD73 expressed in HEK293F cells using [15N]5-AMP as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human CD73 using AMP as substrate incubated for 90 mins by malachite green colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human CD73 using AMP as substrate incubated for 120 mins by CellTiter-Glo assayMore data for this Ligand-Target Pair