BDBM18137 AMP::CHEMBL752::US11185100, TABLE 7.3::[(2R,3S,4R,5R)-5-adenin-9-yl-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate;hydrate::adenosine 5 -monophosphate::{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
InChI Key InChIKey=UDMBCSSLTHHNCD-KQYNXXCUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 18137
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataKi: 0.230nM Kd: 1.13nM Koff: 4.43E+6s-1Assay Description:Association rate constant for the interaction between inhibitor and HIV-1 proteaseMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKd: 3.70E+3nMAssay Description:Binding affinity to recombinant human AMPK alpha1/beta1/gamma1 by SPR binding assayMore data for this Ligand-Target Pair
Target2-dehydropantoate 2-reductase(Escherichia coli (strain K12))
University Chemical Laboratory
Curated by ChEMBL
University Chemical Laboratory
Curated by ChEMBL
Affinity DataKd: >5.00E+6nMAssay Description:Binding affinity to Escherichia coli KPRMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataKd: 1.20E+5nMAssay Description:Binding affinity to recombinant human biotinylated N-terminal GST-tagged autophosphorylated TAK1 (1 to 303 residues) fused with TAB1 (437 to 504 resi...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataKd: 3.70E+5nMAssay Description:Binding affinity to recombinant human biotinylated N-terminal GST-tagged non-autophosphorylated TAK1 (1 to 303 residues) fused with TAB1 (437 to 504 ...More data for this Ligand-Target Pair