BDBM18138 2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]ethan-1-one::5-O-[N-(L-glycyl)sulfamoyl]adenosine::GSAd::Glycine sulfamoyl adenosine
SMILES NCC(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChI Key InChIKey=AMWPZASLDLLQFT-JJNLEZRASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 18138
Affinity DataKi: 50nM ΔG°: -9.95kcal/mole IC50: 2.00E+3nM Kd: 270nMpH: 7.5 T: 2°CAssay Description:Aminoacyl-tRNA synthetase assays were measuring the incorporation of [14C] amino acid into tRNA.More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 18138
ITC DataΔG°: -8.93kcal/mole −TΔS°: 35.6kcal/mole ΔH°: -44.7kcal/mole logk: 3.70E+6
pH: 7.2 T: 24.85°C
pH: 7.2 T: 24.85°C