BDBM182760 US9145412, Table 1, Compound 47

SMILES Nc1ccc(cc1NC(=O)c1cnc2n(CCN3CCOCC3)c(cc2c1)C1CC1)-c1cccs1

InChI Key InChIKey=VVACXVTWNRYQCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 182760   

TargetHistone deacetylase 1(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM182760(US9145412, Table 1, Compound 47)
Affinity DataIC50:  6nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM182760(US9145412, Table 1, Compound 47)
Affinity DataIC50:  445nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM182760(US9145412, Table 1, Compound 47)
Affinity DataIC50:  36nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent