BDBM18868 3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]benzoic acid::dichloro benzoic acid, 11b

SMILES CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)C(O)=O)ccc1O

InChI Key InChIKey=TVQYCFFCYRSFQF-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18868   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)
Affinity DataIC50:  130nM EC50:  190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)
Affinity DataIC50:  21nM EC50:  150nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)
Affinity DataIC50:  20.9nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)
Affinity DataIC50:  129nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)
Affinity DataIC50:  20.9nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed