BDBM18903 2-[3,5-dibromo-4-(2-ethylbutoxy)phenyl]acetic acid::3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9f

SMILES CCC(CC)COc1c(Br)cc(CC(O)=O)cc1Br

InChI Key InChIKey=WDJZIEHFYCTEMU-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18903   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18903(2-[3,5-dibromo-4-(2-ethylbutoxy)phenyl]acetic acid...)
Affinity DataIC50:  6.90E+3nM EC50:  0.820nMpH: 7.0 T: 2°CAssay Description:IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18903(2-[3,5-dibromo-4-(2-ethylbutoxy)phenyl]acetic acid...)
Affinity DataIC50:  800nM EC50:  0.700nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18903(2-[3,5-dibromo-4-(2-ethylbutoxy)phenyl]acetic acid...)
Affinity DataIC50:  794nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18903(2-[3,5-dibromo-4-(2-ethylbutoxy)phenyl]acetic acid...)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18903(2-[3,5-dibromo-4-(2-ethylbutoxy)phenyl]acetic acid...)
Affinity DataIC50:  794nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed