BDBM18926 2-{3,5-dichloro-4-[4-hydroxy-3-(3-methoxyphenyl)phenoxy]phenyl}acetic acid::4-hydroxy thyromimetic, 9h

SMILES COc1cccc(c1)-c1cc(Oc2c(Cl)cc(CC(O)=O)cc2Cl)ccc1O

InChI Key InChIKey=GHFDFTOECTVGNW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18926   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18926(2-{3,5-dichloro-4-[4-hydroxy-3-(3-methoxyphenyl)ph...)
Affinity DataIC50:  297nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18926(2-{3,5-dichloro-4-[4-hydroxy-3-(3-methoxyphenyl)ph...)
Affinity DataIC50:  11nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18926(2-{3,5-dichloro-4-[4-hydroxy-3-(3-methoxyphenyl)ph...)
Affinity DataIC50:  11.0nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18926(2-{3,5-dichloro-4-[4-hydroxy-3-(3-methoxyphenyl)ph...)
Affinity DataIC50:  295nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18926(2-{3,5-dichloro-4-[4-hydroxy-3-(3-methoxyphenyl)ph...)
Affinity DataIC50:  11.0nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed