BDBM189770 US11369599, Compound 341::US9174982, 341

SMILES CC1(O)CCC(COc2ncc(cc2Cl)S(=O)(=O)NC(=O)c2ccc(cc2Oc2cnc3[nH]ccc3c2)N2CCN(CC3=C(CC4(CC4)CC3)c3ccc(Cl)cc3)CC2)CC1

InChI Key InChIKey=GCHGWBYYMDDACZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189770   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM189770(US11369599, Compound 341 | US9174982, 341)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM189770(US11369599, Compound 341 | US9174982, 341)
Affinity DataKi: <0.0100nM ΔG°: <-15.0kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails US Patent