BDBM19125 (1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-7-[(1S)-1-(dimethylamino)ethyl]-8-hydroxy-6,10,15-trimethyl-18-(propan-2-yl)-17,19-diazahexacyclo[12.8.0.0^{1,3}.0^{3,11}.0^{6,10}.0^{15,20}]docos-18-en-4-one::pyrimidine, 26a

SMILES [H][C@@]12CC[C@]3([H])[C@]4(C[C@@]14C(=O)C[C@]1(C)[C@@H]([C@H](C)N(C)C)[C@H](O)C[C@@]21C)CC[C@@H]1N=C(NC[C@@]31C)C(C)C

InChI Key InChIKey=SFXVFHUGPHQWAG-PDIVMOMKSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 19125   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Cnrs

LigandPNGBDBM19125((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-7-[(1S)-1-(di...)
Affinity DataIC50:  18nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19125((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-7-[(1S)-1-(di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BuChE activity was determined by the spectroscopic method of Ellman using butyrylthiocholine iodide as substrate, in 96-well microtiter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Cnrs

LigandPNGBDBM19125((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-7-[(1S)-1-(di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by spectroscopic Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Cnrs

LigandPNGBDBM19125((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-7-[(1S)-1-(di...)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19125((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-7-[(1S)-1-(di...)
Affinity DataIC50:  3.11E+3nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Cnrs

LigandPNGBDBM19125((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-7-[(1S)-1-(di...)
Affinity DataIC50:  2nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed