BDBM19282 2-fluoro-N-[2-(3-methanesulfonylphenyl)propan-2-yl]-9-oxo-9,10-dihydroacridine-3-carboxamide::Acridone-Based Inhibitor, 4f

SMILES CC(C)(NC(=O)c1cc2[nH]c3ccccc3c(=O)c2cc1F)c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=HPGUXRZIRNCJBJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19282   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19282(2-fluoro-N-[2-(3-methanesulfonylphenyl)propan-2-yl...)
Affinity DataIC50:  12nM EC50:  580nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed