BDBM193803 US9670209, Compound 313 1-((R)-3-((1R,3R,58)-3-(2-methoxyethyl)-8-azabicyclo[3.2.1]octan-8-yl)-2-methylpropyl)-6-methoxy-1H-indazole

SMILES COCC[C@@H]1C[C@@H]2CC[C@H](C1)N2C[C@@H](C)Cn1ncc2ccc(OC)cc12

InChI Key InChIKey=DGORWGKJIHHKIC-IZBJGVDFSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193803   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193803(US9670209, Compound 313 1-((R)-3-((1R,3R,58)-3-(2-...)
Affinity DataEC50:  50nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193803(US9670209, Compound 313 1-((R)-3-((1R,3R,58)-3-(2-...)
Affinity DataEC50:  6.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent