BDBM194227 US9200006, 5

SMILES CN1CCN(CC1)c1nc(c(F)s1)-c1ccc(cc1)C(=O)N[C@@H](C1CCCC1)C(=O)N1C[C@@H](C#C)C2OCC(=O)C12

InChI Key InChIKey=DEMUCOOCKQGXOE-NJHUVSBTSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 194227   

TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194227(US9200006, 5)
Affinity DataKi:  0.600nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194227(US9200006, 5)
Affinity DataKi:  1.17E+3nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194227(US9200006, 5)
Affinity DataKi:  2.90E+3nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent