BDBM194491 US9200020, Table 1, Compound 2
SMILES Nc1nc2n(CCNCCP(O)(O)=O)c[nH]c2c(=O)[nH]1
InChI Key InChIKey=HSUMAJMPYOXLHP-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 194491
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland
US Patent
The University of Queensland
US Patent
Affinity DataKi: 3.00E+3nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland
US Patent
The University of Queensland
US Patent
Affinity DataKi: 1.60E+4nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair