BDBM196506 US9212165, 3

SMILES Fc1cccc(c1)C#CC12CCC(C1)(CCC2)NC(=O)c1cnccn1

InChI Key InChIKey=XXTYQEKUMZLRNC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196506   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM196506(US9212165, 3)
Affinity DataKi:  3nM ΔG°:  -11.6kcal/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM196506(US9212165, 3)
Affinity DataIC50:  1.20nMpH: 7.4Assay Description:The rmGluR5 or hmGluR5 was stably expressed in a HEK 293 cell line and gown in Dulbecco's Modified Eagle Medium (DMEM) (Invitrogen, Carlsbad, Cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent