BDBM196506 US9212165, 3
SMILES Fc1cccc(c1)C#CC12CCC(C1)(CCC2)NC(=O)c1cnccn1
InChI Key InChIKey=XXTYQEKUMZLRNC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 196506
Affinity DataKi: 3nM ΔG°: -11.6kcal/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMpH: 7.4Assay Description:The rmGluR5 or hmGluR5 was stably expressed in a HEK 293 cell line and gown in Dulbecco's Modified Eagle Medium (DMEM) (Invitrogen, Carlsbad, Cal...More data for this Ligand-Target Pair