BDBM199945 US9226923, 3

SMILES C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CC2(C1)CCNCC2)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=MXQDRRGPOHEUMT-CQSZACIVSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 199945   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Nanjing Allgen Pharma

US Patent
LigandPNGBDBM199945(US9226923, 3)
Affinity DataIC50:  1.20nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Nanjing Allgen Pharma

US Patent
LigandPNGBDBM199945(US9226923, 3)
Affinity DataIC50:  8.90nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Nanjing Allgen Pharma

US Patent
LigandPNGBDBM199945(US9226923, 3)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Nanjing Allgen Pharma

US Patent
LigandPNGBDBM199945(US9226923, 3)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Nanjing Allgen Pharma

US Patent
LigandPNGBDBM199945(US9226923, 3)
Affinity DataIC50:  1.80nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Nanjing Allgen Pharma

US Patent
LigandPNGBDBM199945(US9226923, 3)
Affinity DataIC50: <1.20nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ...More data for this Ligand-Target Pair
In DepthDetails US Patent