BDBM200430 US9227969, 58

SMILES Cc1nc2cnc3cc(F)c(cc3c2n1[C@H]1CCN(CC#N)C[C@@H]1F)-c1ccc(Oc2nccc(C)n2)cc1Cl

InChI Key InChIKey=MBCDKSSXEBSIEN-IGKIAQTJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200430   

LigandPNGBDBM200430(US9227969, 58)
Affinity DataIC50:  3nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent