BDBM2015 2-ethyl-5-(5-methoxy-1H-indol-3-yl)-9-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one::2-indolyl dipyridodiazepinone 7b::5,11-Dihydro-11-ethyl-2-(5-methoxyindol-3-yl)-5-methyl-6H-dipyrido[3,2-b:2 ,3 -e][1,4]diazepin-6-one
SMILES CCN1c2nc(ccc2N(C)C(=O)c2cccnc12)-c1c[nH]c2ccc(OC)cc12
InChI Key InChIKey=FAUYKFLHHWFNGE-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 2015
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 200nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 230nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,Y787L]/[600-1155,Y787L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 730nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,P835L]/[600-1155,P835L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 404nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 3.09E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,G789A]/[600-1155,G789A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 600nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,K702N]/[600-1155,K702N](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 935nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair