BDBM202581 US10035761, Compound 7g::US9238625, 7g

SMILES CCOCCCCNC(CC(C)C)C1(CCC1)c1ccc(SC)cc1

InChI Key InChIKey=OZMCXSBQOWTTBK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 202581   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202581(US10035761, Compound 7g | US9238625, 7g)
Affinity DataKi:  2.99nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202581(US10035761, Compound 7g | US9238625, 7g)
Affinity DataKi:  2.99nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Revivia Pharmaceuticals

US Patent
LigandPNGBDBM202581(US10035761, Compound 7g | US9238625, 7g)
Affinity DataKi:  37.2nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Revivia Pharmaceuticals

US Patent
LigandPNGBDBM202581(US10035761, Compound 7g | US9238625, 7g)
Affinity DataKi:  37.2nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Revivia Pharmaceuticals

US Patent
LigandPNGBDBM202581(US10035761, Compound 7g | US9238625, 7g)
Affinity DataKi:  92nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Revivia Pharmaceuticals

US Patent
LigandPNGBDBM202581(US10035761, Compound 7g | US9238625, 7g)
Affinity DataKi:  92.0nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent