BDBM202603 US9242943, 12
SMILES C[C@]1(COCC(N)=N1)c1cc(NCCC(F)(F)F)ccc1F
InChI Key InChIKey=YHBCCGYRJHZRIT-ZDUSSCGKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 202603
Affinity DataIC50: 2.90E+3nMAssay Description:The assay uses the principle of inhibition of human TMEM27 cleavage by endogenous cellular BACE2 in the Ins1e rat cell line and shedding from the cel...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:DNA of the human APP wt gene (APP695) were used to assess the potency of the compounds in a cellular assay. The cells were seeded in 96-well microtit...More data for this Ligand-Target Pair