BDBM202610 US9242943, 19

SMILES C[C@]1(COCC(N)=N1)c1cc(N[C@H]2CCC[C@@H]2O)ccc1F

InChI Key InChIKey=RWCZTUDBYGQJTK-DZKIICNBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202610   

TargetBeta-secretase 2(Homo sapiens (Human))
Siena Biotech

US Patent
LigandPNGBDBM202610(US9242943, 19)
Affinity DataIC50:  3.42E+3nMAssay Description:The assay uses the principle of inhibition of human TMEM27 cleavage by endogenous cellular BACE2 in the Ins1e rat cell line and shedding from the cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Siena Biotech

US Patent
LigandPNGBDBM202610(US9242943, 19)
Affinity DataIC50:  1.21E+3nMAssay Description:DNA of the human APP wt gene (APP695) were used to assess the potency of the compounds in a cellular assay. The cells were seeded in 96-well microtit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent