BDBM202627 US9242943, 36

SMILES CC1(COCC(N)=N1)c1cccc(Nc2cc(F)cc3cc(Cl)cnc23)c1

InChI Key InChIKey=WWCXRNBXEBTLSG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 202627   

TargetBeta-secretase 1(Homo sapiens (Human))
Siena Biotech

US Patent
LigandPNGBDBM202627(US9242943, 36)
Affinity DataIC50:  250nMAssay Description:DNA of the human APP wt gene (APP695) were used to assess the potency of the compounds in a cellular assay. The cells were seeded in 96-well microtit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin D(Homo sapiens (Human))
Siena Biotech

US Patent
LigandPNGBDBM202627(US9242943, 36)
Affinity DataIC50:  2.60E+3nMpH: 5.5 T: 2°CAssay Description:A substrate peptide is labeled at the N-terminus with tryptophan and at the C-terminus with the fluorophore MR121 (for cathepsin D the 10 amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin E(Homo sapiens (Human))
Siena Biotech

US Patent
LigandPNGBDBM202627(US9242943, 36)
Affinity DataIC50:  5.00E+3nMpH: 5.5 T: 2°CAssay Description:A substrate peptide is labeled at the N-terminus with tryptophan and at the C-terminus with the fluorophore MR121 (for cathepsin D the 10 amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent