BDBM202627 US9242943, 36
SMILES CC1(COCC(N)=N1)c1cccc(Nc2cc(F)cc3cc(Cl)cnc23)c1
InChI Key InChIKey=WWCXRNBXEBTLSG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 202627
Affinity DataIC50: 250nMAssay Description:DNA of the human APP wt gene (APP695) were used to assess the potency of the compounds in a cellular assay. The cells were seeded in 96-well microtit...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMpH: 5.5 T: 2°CAssay Description:A substrate peptide is labeled at the N-terminus with tryptophan and at the C-terminus with the fluorophore MR121 (for cathepsin D the 10 amino acid ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMpH: 5.5 T: 2°CAssay Description:A substrate peptide is labeled at the N-terminus with tryptophan and at the C-terminus with the fluorophore MR121 (for cathepsin D the 10 amino acid ...More data for this Ligand-Target Pair