BDBM205484 Cytotoxic conjugates, 1
SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O[C@H]([C@@H](NC(=O)c3ccccc3)c3ccccc3)C(=O)O[C@H]3C[C@@]4(O)[C@@H](OC(=O)c5ccccc5)[C@@H]5[C@@]6(CO[C@@H]6C[C@H](O)[C@@]5(C)C(=O)[C@H](OC(C)=O)C(=C3C)C4(C)C)OC(C)=O)c2c1
InChI Key InChIKey=UCXHYGUNDHFQNU-QOKMLCIUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 205484
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine
Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine
Affinity DataIC50: >2.50E+4nMAssay Description:Each molecule was evaluated for its ability to inhibit purified mouse COX-2 or ovine COX-1 using a previously described assay. [Kalgutkar et al, J. M...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine
Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine
Affinity DataIC50: >2.50E+4nMAssay Description:Each molecule was evaluated for its ability to inhibit purified mouse COX-2 or ovine COX-1 using a previously described assay. [Kalgutkar et al, J. M...More data for this Ligand-Target Pair