BDBM206769 (S,R)-2::US9492405, (S,R)-2

SMILES COc1cccc(C[C@@H](C)NC[C@@H](O)c2cc(O)cc(O)c2)c1

InChI Key InChIKey=LGDWSGQDAWEKPG-KZULUSFZSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 206769   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM206769( (S,R)-2 | US9492405, (S,R)-2)
Affinity DataKi:  5.27E+3nM ΔG°:  -6.69kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM206769( (S,R)-2 | US9492405, (S,R)-2)
Affinity DataKi:  3.34E+4nM ΔG°:  -5.67kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM206769( (S,R)-2 | US9492405, (S,R)-2)
Affinity DataKd:  5.25E+3nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent