BDBM20746 8-[(2-iodo-5-methoxyphenyl)sulfanyl]-9-(4-methylpent-3-en-1-yl)-9H-purin-6-amine::Homoprenyl analogue, 23

SMILES [#6]-[#8]-c1ccc(I)c(-[#16]-c2nc3c(-[#7])ncnc3n2-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c1

InChI Key InChIKey=WLTOIVIRGVHOAN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20746   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Conforma Therapeutics

LigandPNGBDBM20746(8-[(2-iodo-5-methoxyphenyl)sulfanyl]-9-(4-methylpe...)
Affinity DataEC50:  370nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed