BDBM207977 N-methyl-4,5-di(4-chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-5-hydroxy-1,5-dihydro-2H-pyrrol-2-one (1b)

SMILES CN1C(=O)C(=C(Cc2ccc(Cl)cc2)C1(O)Cc1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12

InChI Key

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207977   

TargetE3 ubiquitin-protein ligase Mdm2 [1-118](Homo sapiens (Human))
Jagiellonian University

LigandPNGBDBM207977(N-methyl-4,5-di(4-chlorobenzyl)-3-(6-chloro-1H-ind...)
Affinity DataKd:  5.60E+4nMpH: 7.4 T: 2°CAssay Description:Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed