BDBM207981 N-methyl-5-(4-chlorobenzyl)-3-(6-chloro-1-methyl-1H-indol-3-yl)-4-(4-chlorophenyl)-5-hydroxy-1,5-dihydro-2H-pyrrol-2-one (1f)
SMILES CN1C(=O)C(=C(c2ccc(Cl)cc2)C1(O)Cc1ccc(Cl)cc1)c1cn(C)c2cc(Cl)ccc12
InChI Key InChIKey=WOBXBPKIDBJQJT-UHFFFAOYSA-N
Data 2 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 207981
Affinity DataKd: 3.04E+4nMpH: 7.4 T: 2°CAssay Description:MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...More data for this Ligand-Target Pair
Affinity DataKd: 2.46E+5nMpH: 7.4 T: 2°CAssay Description:Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...More data for this Ligand-Target Pair