BDBM207987 4-(4-chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-5-(4-fluorobenzyl)-5-hydroxy-1,5-dihydro-2H-furan-2-one (2d)

SMILES OC1(Cc2ccc(F)cc2)OC(=O)C(=C1Cc1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12

InChI Key

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207987   

TargetE3 ubiquitin-protein ligase Mdm2 [1-118,T47W](Homo sapiens (Human))
Jagiellonian University

LigandPNGBDBM207987(4-(4-chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-5-(4...)
Affinity DataKd:  2.60E+4nMpH: 7.4 T: 2°CAssay Description:MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed