BDBM209393 US9266890, I-1

SMILES CN1c2cnc(Nc3ccc(cn3)N3CCC(O)CC3)nc2N(CCC1=O)C1CCCC1

InChI Key InChIKey=WUDDKNUPJTYVAB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209393   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM209393(US9266890, I-1)
Affinity DataKd:  49nMAssay Description:In vitro Plk1 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM209393(US9266890, I-1)
Affinity DataIC50:  891nMT: 2°CAssay Description:Kinase reactions were carried out at room temperature with the following components: 1× kinase reaction buffer, 5 μg/mL (40 nM) Mps1 kinase, 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent