BDBM209755 US9273033, 55
SMILES CCc1cc(cn(C)c1=O)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc(C)cn1
InChI Key InChIKey=BOWJHZYYANZOSF-MOPGFXCFSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 209755
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.347nM ΔG°: -12.9kcal/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP FP kit supplied by Molecular Devices, Sunnyv...More data for this Ligand-Target Pair