BDBM21147 (3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-amino-3-formamidopropanoic acid]-3-[4-(sulfooxy)phenyl]propanamido]-4-(methylsulfanyl)butanamido]acetamido}-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid::CCK-8::CCK-8(SO3)::CHEMBL1121::H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2::SINCALIDE::Syncalide::[125I]CCK-8
SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key InChIKey=IZTQOLKUZKXIRV-YRVFCXMDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 21147
Affinity DataKi: 0.280nMAssay Description:Inhibition of [3H]pCCK-8 binding to Cholecystokinin type A receptor of Guinea pig pancreatic membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of 0.2 nM [3H]-pCCK-8 from guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to CCK-8 receptor of guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of 0.1 nM [3H]-pCCK-8 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity against cholecystokinin type B receptor on guinea pig cortex.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]pCCK-8 from cholecystokinin type B receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Mus musculus)
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Potency in displacing [3H]propionyl-Cholecystokinin from mouse brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Compound was tested for binding affinity against Cholecystokinin type B receptor expressed in CHO cells on the rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Ability to displace 1 nM [3H]pCCK-8 from Cholecystokinin type A receptor in guinea pig pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Affinity to inhibit [3H]pCCK-8 specific binding on rat brain Cholecystokinin type B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataKi: 0.640nMAssay Description:Inhibition of [3H]pCCK-8 binding to Guinea pig cortex membrane Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Ability to displace 1 nM [3H]pCCK-8 from rat Cholecystokinin type B receptor stably expressing in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Compound was tested for binding affinity against CCK1 (cholecystokinin) receptor on guinea pig pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]-pCCK-8 from cholecystokinin-A receptor in guinea pig pancreatic membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 0.630nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
Affinity DataEC50: 0.630nMAssay Description:Effective concentration for the stimulation of Inositol Phosphate accumulation in CHO cells expressing wild-type Cholecystokinin type B receptorMore data for this Ligand-Target Pair