BDBM21165 1-{[4-bromo-2-(2,4-dichlorophenyl)oxolan-2-yl]methyl}-1H-1,2,4-triazole::Triazole-based ligand, 16

SMILES Clc1ccc(c(Cl)c1)C1(Cn2cncn2)CC(Br)CO1

InChI Key InChIKey=HJJVPARKXDDIQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21165   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21165(1-{[4-bromo-2-(2,4-dichlorophenyl)oxolan-2-yl]meth...)
Affinity DataIC50:  8.10E+3nMAssay Description:The inhibition of recombinant human CYP2C9 was measured as the ability to perform a demethylation of 7-methoxy-4-trifluoromethylcoumarin (MFC). Befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21165(1-{[4-bromo-2-(2,4-dichlorophenyl)oxolan-2-yl]meth...)
Affinity DataIC50:  130nMpH: 7.4 T: 2°CAssay Description:The inhibition of recombinant human CYP3A4 was measured as the ability to perform a debenzylation of 7-benzyloxy-4-trifluoromethylcoumarin (BFC). Bef...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed