BDBM21172 CHEMBL251975::N-[2-(furan-2-yl)-6-(1H-pyrazol-1-yl)pyrimidin-4-yl]-2-(4-methylpiperazin-1-yl)acetamide::Pyrimidine analogue, 1
SMILES CN1CCN(CC(=O)Nc2cc(nc(n2)-c2ccco2)-n2cccn2)CC1
InChI Key InChIKey=QMZAMLTVEASZQQ-UHFFFAOYSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 21172
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nM ΔG°: -11.6kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]ZM241385 from rat recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]MRS1754 from human adenosine A2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 266nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Displacement of [3H]DPCPX form human adenosine A1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 270nM ΔG°: -8.86kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
Affinity DataKi: 660nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptorMore data for this Ligand-Target Pair