BDBM21185 2-(4-methylpiperazin-1-yl)-N-[6-(1H-pyrazol-1-yl)-2-(1,3-thiazol-2-yl)pyrimidin-4-yl]acetamide::Pyrimidine analogue, 37

SMILES CN1CCN(CC(=O)Nc2cc(nc(n2)-c2nccs2)-n2cccn2)CC1

InChI Key InChIKey=PSCBVZXHPONWAG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21185   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Neuroscience

LigandPNGBDBM21185(2-(4-methylpiperazin-1-yl)-N-[6-(1H-pyrazol-1-yl)-...)
Affinity DataKi:  17nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Neuroscience

LigandPNGBDBM21185(2-(4-methylpiperazin-1-yl)-N-[6-(1H-pyrazol-1-yl)-...)
Affinity DataKi:  850nM ΔG°:  -8.19kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed