BDBM213222 (S)-1-(3-((4-((Dimethylamino)methyl)-6-(thiazolo[5,4-b]pyridin-2-ylamino)pyridin-2-yl)amino)pyrrolidin-1-yl)prop-2-en-1-one (11)

SMILES CN(C)Cc1cc(N[C@H]2CCN(C2)C(=O)C=C)nc(Nc2nc3cccnc3s2)c1

InChI Key InChIKey=MXCYYCUMOMWODQ-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 213222   

TargetTyrosine-protein kinase ITK/TSK [357-620,Y512E](Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM213222((S)-1-(3-((4-((Dimethylamino)methyl)-6-(thiazolo[5...)
Affinity DataIC50:  32nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed