BDBM213748 US9284299, PKF115-584::US9738628, Compound PKF115-584

SMILES COc1cc(O)c2c3c1c1c(OC)cc(O)c4c1c(c(C[C@@H](C)OC(=O)c1ccccc1)c(OC)c4=O)c3c(C[C@@H](C)OC(=O)Oc1ccc(O)cc1)c(OC)c2=O

InChI Key InChIKey=SRJYZPCBWDVSGO-NHCUHLMSSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 213748   

TargetCadherin-1 [819-873]/Catenin beta-1 [138-686](Homo sapiens (Human))
University of Utah Research Foundation

US Patent
LigandPNGBDBM213748(US9284299, PKF115-584 | US9738628, Compound PKF115...)
Affinity DataKi:  1.30E+4nM ΔG°:  -6.66kcal/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCatenin beta-1 [138-686]/Transcription factor 4 [7-51](Homo sapiens (Human))
University of Utah Research Foundation

US Patent
LigandPNGBDBM213748(US9284299, PKF115-584 | US9738628, Compound PKF115...)
Affinity DataKi:  1.78E+4nM ΔG°:  -6.48kcal/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCatenin beta-1 [138-686](Homo sapiens (Human))
University of Utah Research Foundation

US Patent
LigandPNGBDBM213748(US9284299, PKF115-584 | US9738628, Compound PKF115...)
Affinity DataKi:  1.78E+4nMAssay Description:Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCatenin beta-1 [138-686](Homo sapiens (Human))
University of Utah Research Foundation

US Patent
LigandPNGBDBM213748(US9284299, PKF115-584 | US9738628, Compound PKF115...)
Affinity DataKi:  1.78E+4nM ΔG°:  -6.48kcal/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686](Homo sapiens (Human))
University of Utah Research Foundation

US Patent
LigandPNGBDBM213748(US9284299, PKF115-584 | US9738628, Compound PKF115...)
Affinity DataKi:  5.39E+4nM ΔG°:  -5.82kcal/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent