BDBM21724 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid::3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid::CHEMBL318457::GW-4064
SMILES CC(C)c1onc(c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl
InChI Key InChIKey=BYTNEISLBIENSA-MDZDMXLPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 21724
TargetBile acid receptor(Homo sapiens (Human))
Southern Medical University Biomedical Research Center
Curated by ChEMBL
Southern Medical University Biomedical Research Center
Curated by ChEMBL
Affinity DataEC50: 27nMAssay Description:Agonist activity at FXR-LBD (unknown origin) assessed as induction of coactivator SRC-1 peptide recruitment measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Southern Medical University Biomedical Research Center
Curated by ChEMBL
Southern Medical University Biomedical Research Center
Curated by ChEMBL
Affinity DataEC50: 232nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells by luciferase reporter assayMore data for this Ligand-Target Pair